Intravenous Alteplase for Stroke
نویسندگان
چکیده
منابع مشابه
Aspiration Thrombectomy After Intravenous Alteplase Versus Intravenous Alteplase Alone.
BACKGROUND AND PURPOSE Thrombectomy, primarily with stent retrievers with or without adjunctive aspiration, provided clinical benefit across multiple prospective randomized trials. Whether this benefit is exclusive to stent retrievers is unclear. METHODS THERAPY (The Randomized, Concurrent Controlled Trial to Assess the Penumbra System's Safety and Effectiveness in the Treatment of Acute Stro...
متن کاملUnequal access to treatment with intravenous alteplase for women with acute ischemic stroke.
BACKGROUND AND PURPOSE A recent meta-analysis showed that women with acute ischemic stroke are less likely to receive treatment with intravenous alteplase than men. The aim of this study was to assess sex differences in treatment with intravenous alteplase and to explore the reasons for these differences. METHODS We analyzed data from the Promoting Acute Thrombolysis for Ischaemic Stroke (PRA...
متن کاملThrombolysis With 0.6 mg/kg Intravenous Alteplase for Acute Ischemic Stroke in Routine Clinical Practice
Background and Purpose—In Japan, alteplase at 0.6 mg/kg was approved in October 2005 for use within 3 hours of stroke onset by the Ministry of Health, Labor and Welfare (MHLW). The aim of the Japan post-Marketing Alteplase Registration Study (J-MARS), which was requested by MHLW at the time of approval, was to assess the safety and efficacy of 0.6 mg/kg alteplase in routine clinical practice fo...
متن کاملIntravenous alteplase for stroke in those older than 80 years old.
BACKGROUND AND PURPOSE Risks and benefits of intravenous thrombolysis for patients with stroke > 80 years of age are unclear. We examined outcomes and symptomatic intracerebral hemorrhage rates in ≤ 80- and > 80-year-old patients in the Safe Implementation of Treatment in Stroke International Stroke Thrombolysis Register. METHODS We compared mortality and independence (modified Rankin Scale 0...
متن کاملEffectiveness of thrombolysis with intravenous alteplase for acute ischemic stroke in older adults.
To the Editor: Thrombolysis with intravenous alteplase is widely accepted as an effective treatment for individuals with acute ischemic stroke, but few individuals aged 80 and older are treated with alteplase. The risk:benefit ratio of thrombolysis might be less favorable with older age because of a higher risk of adverse events and lower efficacy. Outcomes in older adults treated with alteplas...
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ژورنال
عنوان ژورنال: Stroke
سال: 2007
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.106.480566